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Bone density measurements were never meant to be treatment guidelines

For years we have known that bone density does not itself predict fracture, yet how many men and women have been told, and continue to be told, that they should take osteoporosis drugs based on their bone density? So I was delighted to hear noted osteoporosis researcher Dr. Steven Cummings declare that bone density testing was never intended to serve as a guide to treatment. He made this statement on September 11, 2009 at the annual meeting of the American Society of Bone Mineral Research in Denver.

As Dr. Cummings detailed, the T score definitions of osteoporosis (defined as -2.5 T or more) and osteopenia (defined as -1 T or more) were developed by World Health Organization Committee in the face of expanding bone mineral density testing. Researchers felt the need to define what was “normal” bone density, so they developed the “T scores” rating system distinguish how similar one’s bone density was to that of a young person of the same sex. These definitions were supposed to be guidelines for establishing normal ranges, not signals of a need for treatment with bone drugs.

Dr. Cummings went on to suggest, as I have suggested before, that treatment guidelines should be based on an individual evaluation of multiple risk factors as is offered in the WHO's FRAX tool, or better yet, in a more comprehensive fracture risk assessment like the one available on this site.

He also reminded his colleagues that another valuable way to assess risk of future fracture is by detection of previous fractures. While you well know if you have had a hip or wrist fracture, you may not know if you have a deformity, or fracture, of a vertebral body in the spine. An important new tool for detection of vertebral fractures is the “Vertebral Fracture Assessment" also known as a “Vertebral Deformity Assessment.” These tests, using either a spinal x-ray or a special picture from the bone density test can reveal of you have “hidden” vertebral fractures. If no deformities are found, no treatment is needed, but if such hidden fractures are found, taking action to strengthen bone is necessary. Existing fracture is the ultimate proof of bone weakness, and having such a fracture puts you at higher risk for further fractures.

Here at the Center for Better Bones, we try to give clients a realistic understanding of their fracture risk so that they know whether they need to take steps to improve their bone health. And we have a complete program that we tailor to their individual needs to help them do exactly that, without resorting to expensive bone drugs with unpleasant and unhealthy side effects. You can learn more about our ideas regarding natural bone health by reading the articles on betterbones.com.

Reference:

Cumming, Steven, “Identifying People Who Should be Treated to Reduce Fractures”. Presented at the “Osteoporosis: Focus on Fracture Prevention” Symposium, ASBMR Annual Meeting, Denver, 9-11-09.

 

 

We created the Osteo Blast blog as our forum to express opinions and educate the public about natural means of supporting and improving bone health and overall wellness. As part of this forum, we sometimes discuss medical issues and medications, and their effects on bone health in general. However, we cannot advise readers about specific medical issues in this forum. If you wish to obtain advice from Susan E. Brown, PhD, about your specific bone health and nutritional concerns, please visit our Consultations page. Other specific medical questions should be referred to your healthcare provider.

Comments

September 30. 2009 15:50

Dr. Brown,

What is a realistic range (number) as a goal for me to increase my T-score in 6 months to 1 year? I am  a 50 year old post-menopausal woman with a T score -2.5? I'm reading your book and changing my diet, excercise regimen and creating a stressless lifestyle.
Thank-you,
Maire Tashjian

Maire Tashjian

January 4. 2010 09:14

Hi Marie,

Bone density changes very slowly as a rule, but the period right around menopause can be a time of rapid bone loss for many women.
If you can hold density around menopause, that is very good.   Most women lose 8-9% during the menopausal transition. Gaining density at this time takes serious strength training and muscle building along with the other factors you mentioned.
Best wishes, Susan Brown


Susan Brown

January 13. 2010 20:59

Dear Dr.Brown,

Could you send me/print stories in yur newsletter of how woman with epilepsy cope with osteopenia and loss of bone?.    

I have had epilepsy since I was 17.  I am now 65, take fosamax (4-5 yrs now) at Neurologist and Gynecologist's suggestion.  However, the epilepsy drugs deplete bone, that is the real culprit.  I go to the gym at least 5-6 days weekly, take calcium, Vit D, and eat healthy.  
Thank you---NOBODY MENTIONS EPILEPSY & THIS DREADED MEDICATIONS.

kathy jacobs

March 13. 2010 12:42

Hi Kathy,

You are correct about bone damage from epilepsy medications. You are taking good steps, but also think about our Alkaline for Life diet and the full range of the 20 key bone nutrients discussed on our site.

Also some epilepsy meds might be more harmful to bone than others.  Dr. G Farhat at the Calcium Metabolism and Osteoporosis Program,  American University of Beirut, Lebanon found certain epilepsy medications are association with lower bone mass than others.  Specifically he reports, "The patients with enzyme-inducing drugs (e.g. phenytoin, phenobarbital, carbamazepine, and primidone) tended to have lower bone mineral density, than those agents that did not induce enzymes (e.g. valproic acid, lamotrigine, clonazepam, gabapentin, topamirate, and ethosuximide". You might ask your doctor about this. http://www.docguide.com/news/content.nsf/news/8525697700573E1885256BC8006266EA.
Finally, at the Center for Better Bones we have been able at times to find the cause of seizures working with the doctors to look at immune responses (delyaed hypersensitivites) and toxic burden.  Correcting the cause of the seizures and the need for such medications, if at all possible, is the ideal path,
Best wishes, Susan

Susan Brown

September 10. 2010 19:49

Thank you Dr. Brown for your comment about valporic acid.  I take it for migraines, as it seems to be the only thing that helps. Also, I recently decided to get braces at the age of 64.  One of the questions my orthodontist asked first was whether or not I took biphosphonates. I was happy to say that I stopped taking them eighteen months ago after reading your website.  I'd rather have my teeth fixed and keep my bones healthy the natural way.

Frieda Devine

October 20. 2010 10:25

Dr. Brown:  I recently had hip replacement surgery and my surgeon told me my bones are like balsom wood.  I was previously diagnosed with a T score of -2.5.  I'm seriously considering taking one of the annual shots to improve bone density.  Isn't the risk of that better than a possible fracture?  I'm looking into Zometa, Prolia and Reclast.  I see my doctor on October 28, 2010 and need to know what to do.
Thank you.

Nancy Nimmo

October 20. 2010 10:54

Nancy, if your fracture risk is very high, then it could well be true that the shots will benefit you, and that the benefit will outweight the potential costs. That said, it's important that you understand that a low DEXA measurement by itself, even in the osteoporotic range, doesn't necessarily mean you're at a high risk for fracture. Many people with osteoporosis don't fracture, while others with normal or slightly low (osteopenic) bone density do--it's all about determining how strong your bones are, rather than how dense they are. Contrary to what your doctor may believe, bone density measurements were never supposed to be used to decide upon treatment regimens, and recommending bone drugs on the basis of a single DEXA measurement is contrary to the Surgeon General's recommendations for osteoporosis treatment. We suggest that you get a better sense of your real fracture risk by taking our fracture risk assessment & bone health profile here: www.betterbones.com/bonehealthprofile/default.aspx (you can print out the questionnaire and the results to bring to your doctor's appointment), then read the following articles to learn more about the pros and cons of different approaches to treating osteoporosis and reducing the risk of fractures: www.betterbones.com/osteoporosis/risks-benefits.aspx (see, especially, the section on the Surgeon General's recommendations), www.betterbones.com/bonefracture/whowillfracture.aspx, and also, www.betterbones.com/osteoporosis/whoneedstestsforosteoporosis.aspx. The last article in this list will help you to understand how to work with your doctor to find out why you have osteoporosis, because here's the thing about bone drugs: they can stop you from continuing to lose bone if you're losing bone, but they won't fix the problem that's causing your bone loss. For that, you need to investigate and find out WHY you're losing bone (massive bone loss is not a normal part of aging, popular "wisdom" notwithstanding). Otherwise, you'll never be able to get off the bone drugs without continuing to lose bone.

Hope this helps!

Managing Editor

October 20. 2010 16:50

Dr. Brown, Can you explain why all of the various tools used to predict risk of osteoporotic fracture only ask if a parent has had a hip fracture?  I have reviewed several including yours and the FRAX tool.  My 89 yr old mother has had a total of 14 fractures, mostly vertebral but also wrist and ribs, and has lost 5" in height. She has never fractured a hip in spite of a few falls over the years. Her hip BMD is in the normal range since a course of Forteo and has never been any worse than osteopenic.  Is there any significance to a parent with multiple non-hip osteoporotic fractures?  Thanks!  Angela

Angela Sokol

October 26. 2010 17:12

Dear Angela.
The fracture risk tools most often use hip fracture because it is easy to document and count hip fractures, as most of those who experience these fractures go to a hospital.  Low-trauma vertebral fractures are also important and a sure sign of osteoporosis, but 2/3 of them go undetected.  Even the person who fractured a vertebral body does not know they have fractured it.  Thus, it is difficult to use spinal fractures in population risk assessment studies.  That your mother had spinal fractures does not mean that you have to experience then, but it does suggest you should undertake a good bone building program like our comprehensive Better Bones Program.  Best wishes for life long strong bones, Susan

Susan Brown

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