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Researchers weigh in: Thin women more likely to experience rapid bone loss in menopause transition

I have shared with you my experiences how thin and worried women often have lower bone mass and tend to lose more bone during the menopausal transition.

But there is still much we can learn about this connection. In fact, I have become so interested in this phenomenon that I recently began my own “Thin Women and Bone Loss” research project.

And researchers around the world are interested in this topic too.

Recently, one Chinese study focusing on bone loss during premenopause, perimenopause, and post-menopause had the novel aspect of looking at how weight and body mass index predicted the likelihood of rapid bone loss during the menopausal transition. In the study, women weighing less than 110 lbs. had 5.5 times the risk of rapid bone loss than women who weighed more than 110 lbs. Among all risk factors, only body weight and body mass index were significantly different between those with rapid bone loss and those with normal bone loss. Thin Chinese women clearly lost more bone during the menopause transition.

These findings were part of a 2010 study following 161 Chinese women, ages 45-55, for five years. During that time, most moved from premenopause into perimenopause and post-menopause. Researchers also found that among these women the most rapid rate of bone loss occurred during the perimenopausal stage of the menopausal transition. This tendency towards rapid bone loss during perimenopause has also been documented among Caucasians by endocrinologist Dr. Jerilynn Prior and others.

Here at the Center for Better Bones we have found both aspects of the study to be true for Caucasians, but our standard for “thin” is more like being less than 120 lbs. We have found thin women who worry excessively seem to undergo more bone loss than those who do not have such a strong tendency to worry.

With the body of research growing about the connection between weight and bones, I want to encourage women — from premenopause and beyond — to remember they can make a measurable difference in their bone health with a comprehensive approach that includes the proper diet, exercise, and supplements.

I look forward to updating you on my research project!

 

Reference Cora, H et al. 2010. Body weight but not serum C-telopeptide predicts rate of bone loss during the menopausal transition. ASBMR poster presentation M00339, Toronto.

We created the Osteo Blast blog as our forum to express opinions and educate the public about natural means of supporting and improving bone health and overall wellness. As part of this forum, we sometimes discuss medical issues and medications, and their effects on bone health in general. However, we cannot advise readers about specific medical issues in this forum. If you wish to obtain advice from Susan E. Brown, PhD, about your specific bone health and nutritional concerns, please visit our Consultations page. Other specific medical questions should be referred to your healthcare provider.

Comments

May 3. 2011 09:32

This is Andrea Flanagan and I have spoken to you, Dr. Susan Brown twice during a telephone conference regarding bone loss and an alkaline diet.  I am a thin type worman who worries a great deal.  You mentioned to me your research project in this area.  I am wondering if I would be a candidage for your research project.  I am 5' 3 1/2" and weigh 105 lbs.  I have great stress and anxiety.  And I have an autoimmune condition.  You have my records and I was wondering if I qualify.  Please contact me one way or the other regarding your research project.  Thank you.  

Andrea Flanagan

May 5. 2011 13:33


I was an elite level cyclist and swimmer from early childhood, and adult ironman competitor, always thin and diagnosed with osteoporosis in my 40s (via dexascan after numerous bone breaks in bike crashes).  I spent a few years figuring out that problem (which led me to your site and blog) but since managed to encounter a different, but related, bone problem.  

Struck by a car two years ago, among many other fractures the head of one femur was separated from the rest of that bone and reattached using a two bolt fixing which after time and PT and TLC, is now in great shape and my orthopedist says is completely healed.  But he warns me that even years later the bone, the round top of the femur inside the hip, can "die" and collapse, and therefore they will continue to monitor me for many years.  

My question is whether this problem of bone death after that sort of trauma is also going to be made less likely by good bone health practises - diet, exercise, stress management - which I have tried to implement in the past several years.  That seems like common sense, but is it also correct?  And are there other things patients like me with that type of bone health concern should be doing?   Are there other situations in which death of a bone occurs?  I had never heard of that happening, but I suppose I think of it like transplanting a branch of a tree - sometimes it takes and sometimes not.   Maybe there are many readers like me who would be interested in hearing about that element of bone health.

- Rick Fleeter (Charlestown, RI)

Rick Fleeter

May 6. 2011 11:34

Hi Andrea,  Thanks for the inquiry.  Right now our research on weigh and bone involves secondary review and analysis of of the existing literature.  My analysis of the data I will try and offer in these blogs and on my site. Best wishes, Susan

Susan E Brown

May 6. 2011 11:57

Hi Rick,
It would be wise of do all the steps of our Better Bones Program, including the 20 key nutrients and the Alkaline for Life Diet and stress reduction.  I would also look into Traditional Chinese Medicine (herbs and acupuncture)  and perhaps Qi Gong.  These ancient sciences understand much more about the flow of nutrients, information and intelligence throughout the body than do we.  For example, I have heard talk of a Chinese herbal formula which is said to help with hip necrosis (should it develop),but prevention is always better.  Best wishes, Susan

Susan E Brown

May 9. 2011 08:56

HI Susan
Will you be doing any research into the effect of anorexia on bone loss. I am 33years old adn have never ever mensturated - even that thought worries me greatly. I follow an alkaline diet and exercise regularly (swimming, cycling, yoga, pilates, walking). Do you think there is any way of increasing my bone mass now?
Best wishes

anonymous

May 9. 2011 09:51

Dear Anonymous,

You absolutely still have the opportunity to increase your bone mass. It's NEVER too late. Here's one article that Susan wrote that may be beneficial, because it discusses some of the issues you face: www.betterbones.com/betterbody/bonehealth-stress-ovulation.aspx. It's important that you recognize that simply by following an alkaline diet and getting regular exercise, you're doing some of the right things, but also be sure you're getting the 20 key nutrients for bone health (see Susan's article here: www.betterbones.com/bonenutrition/20keybonenutrients.aspx) and keep in mind that while exercise is generally good for bone, too much exercise can be harmful, not beneficial, and that you may want to focus on either substituting weight-bearing exercise for one of your cardio routines (walking or cycling) or add weights, in the form of a weighted vest or hand and ankle weights, to your walking. Susan recently put up an article on gaining weight if you're underweight that you might want to look at, too; it's here; www.betterbones.com/bonenutrition/weightgainingforunderweight.aspx

Best of luck to you!

Managing Editor

May 9. 2011 17:49

Did the study make any reference to the rate of bone fractures among these women - which is perhaps a more important measure.  

Laura

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